Klinefelter Syndrome And Fertility
Klinefelter syndrome and fertility. This disorder is one of the most common genetic disorders that affect males. Klinefelter syndrome is a chromosomal condition that. About 30-50 of men with Klinefelter syndrome KS.
An argument for early aggressive hormonal and fertility management. Akm9009medcornelledu Comment in Fertil. Males with Klinefelters Syndrome will have XXY.
The reason for the absence or presence of spermatozoa in half of the men with KS remains unknown. Men with hypogonadism who respond to medical therapy may have a better chance of sperm retrieval. Approximately 3 of all infertile men have Klinefelter syndrome 1 and 14 of non-obstructive azoospermic men have Klinefelter syndrome 3.
Special urologic techniques may help in identifying and retrieving sperm cells for fertility treatments. We present here a case of a 36year-old male who didnt experience any health problems and he was married and had three children. 1Department of Urology Weill Cornell Medical College New York New York USA.
Microdissection testicular sperm extraction is an effective sperm retrieval technique in men with Klinefelters syndrome. SUMMARY ANSWER Current evidence shows that fertility preservation should not be offered to adolescents with KS younger than 16 years because of lower retrieval rates for germ cells by testicular sperm extraction TESE compared with retrieval rates for adolescents and adults between 16 and 30. Until recently it was thought that all males with Klinefelter syndrome were infertile.
Successful fertility treatment for Klinefelters syndrome. Microdissection testicular sperm extraction is an effective sperm retrieval technique in men with Klinefelters syndrome. This can be explored with testicular sperm extraction TESE often performed with a microscope micro-TESE.
The primary features are infertility and small poorly functioning testicles. Having this extra X chromosome will interfere with sexual development which can in turn interfere with fertility.
Should fertility preservation be offered to children with Klinefelter syndrome KS.
Approximately 3 of all infertile men have Klinefelter syndrome 1 and 14 of non-obstructive azoospermic men have Klinefelter syndrome 3. Approximately 3 of all infertile men have Klinefelter syndrome 1 and 14 of non-obstructive azoospermic men have Klinefelter syndrome 3. Males with Klinefelters Syndrome will have XXY. But sperm are found in more than 50 of men with KS. Thus it is important to take this knowledge into consideration when counselling Klinefelter patientsGerm cell degeneration in the testicles of Klinefelter. Klinefelter syndrome KS also known as 47XXY is a syndrome where a male has an additional copy of the X chromosome. The reason for the absence or presence of spermatozoa in half of the men with KS remains unknown. Men with hypogonadism who respond to medical therapy may have a better chance of sperm retrieval. Sometimes symptoms are more evident and may include weaker muscles greater height poor motor coordination less body hair.
This can be explored with testicular sperm extraction TESE often performed with a microscope micro-TESE. But sperm are found in more than 50 of men with KS. The primary features are infertility and small poorly functioning testicles. Klinefelter syndrome KS also known as 47XXY is a syndrome where a male has an additional copy of the X chromosome. Males with Klinefelters Syndrome will have XXY. An argument for early aggressive hormonal and fertility management. Mehta A1 Paduch DA.
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